ChatGPT made two clear errors about mitochondrial DNA. First, when asked about the Anzick-1 burial (a 12,600-year-old Clovis child skeleton from Montana), ChatGPT claimed the mtDNA haplogroup was A2ex. The correct haplogroup is D4h3a — a fundamental error in ancient DNA genetics that a co-author of the Mitotree paper had to correct. Second, when a user asked about tracing their maternal grandfather's mitochondrial DNA, ChatGPT told them they could do it by testing themselves. This is biologically impossible — mitochondrial DNA is inherited exclusively from the mother, so a person can never inherit their paternal grandfather's mtDNA. ChatGPT then congratulated the user for catching the error and 'went on as if nothing happened.' A third-party company also used AI to create a scientifically wrong infographic from the authors' research, placing all non-L haplogroups under L4 — they actually descend from L3.
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